Selective 2′-hydroxyl acylation analyzed by primer extension (SHAPE) chemistries exploit small electrophilic reagents that react with 2′-hydroxyl groups to interrogate RNA structure at ...
This protocol is an extension to: Nat. Protoc. 10, 1643–1669 (2015); doi:10.1038/nprot.2015.103; published online 01 October 2015 RNAs play key roles in many ...
The cellular equivalent of a rough wiring diagram for HIV gives further evidence that the architecture of its genome, not just its sequence, explains how the deadly virus works. Researchers at the ...
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