I don't remember the first time I heard the word "germline," but I do remember when it became a major part of my life. I’m not sure when I first heard the term "germline." I’ve always been a bit of a ...

Patients with stages I to III breast cancer who were seen at a single cancer center between 2010 and 2012, and who agreed to participate in research DNA banking, were included (N = 488). Personal and ...

An estimated 170,000 Australians were diagnosed with cancer in 2025. Many people know the causes of cancer are partly genetic. But how do your genes, which contribute so much of what makes you you, ...

Enhancing PSA-based screening with multiparametric magnetic resonance imaging (MRI) improves detection of prostate cancer among men with germline mutations while reducing unnecessary biopsies. For men ...

Germline BRCA mutations have an adverse impact on both progression-free and overall survival in patients with hormone receptor-positive/HER2-negative metastatic ...

Germline testing can identify hereditary cancer, which leads to implications for family members, cascade testing for relatives, and starting surveillance and prevention measures: Genetic testing in ...

In a study published in Current Biology on August 14, Prof. Miao Wei's team at the Institute of Hydrobiology (IHB) of the Chinese Academy of Sciences and Prof. Zhang Jianzhi's team at the University ...

The rates of germline mutations — genetic changes passed from parents to their offspring — have been estimated for 68 vertebrate animal species using a method involving mother–father–offspring trios.

The Journal of Clinical Oncology podcast, hosted by Dr. Davide Soldato, presents analyses and discussions centered on the latest findings published in ASCO’s esteemed Journal of Clinical Oncology.

A new study from deCODE genetics uses pedigrees and sequence data from 64,806 Icelanders to shed light on the rate and nature of mutations in mitochondrial DNA (mtDNA) and the peculiar dynamics of its ...

By Tarun Sai Lomte Scientists reveal how evolution within our own tissues can drive disease, protect cells, and uncover ...