A collaborative effort among researchers at the Henan Academy of Innovations in Medical Science, Zhengzhou University, and ...

During the process of metastasis, tumor cells inevitably encounter the stimulation of various oxidative stressors, resulting in the fluctuation of intracellular reactive oxygen species (ROS) levels.

Embryonic stem cells (ESCs) exhibit unique chromatin features, including a permissive transcriptional program and an open, decondensed chromatin state. Induced pluripotent stem cells (iPSCs), which ...

Diffuse midline glioma (DMG), H3K27-altered, is a lethal pediatric high-grade tumor, lacking effective treatment options, primarily depending on clinical trials. Epigenetic agent-based immunotherapy ...

Epigenetics, the dynamic regulation of genetic expression, involves complex molecular mechanisms. While the process of gene silencing by methylating the H3K27 position in histones is understood, not ...

Cancer progression and relapse arise not only from genetic evolution but also from dynamic, reversible cell-state transitions that enable malignant cells to ...

In the intricate regulation of inflammation, metabolic reprogramming and posttranslational modification (PTM) have emerged as ...

(koto_feja/Canva) Researchers have developed a novel compound that could transform the way we treat Alzheimer's disease, offering not just a new weapon but potentially a new strategy for battling the ...