DNA, the medium of life, is so deeply associated with the biochemical world that considering its nonbiological applications may seem far-fetched. However, for researchers in the 1980s and 1990s ...

Tunable DNA hairpin springs stretch millions of protein copies under piconewton tension, enabling bulk biochemical discovery of binding partners invisible to single-molecule techniques.

One of the challenges of fighting pancreatic cancer is finding ways to penetrate the organ's dense tissue to define the margins between malignant and normal tissue. A new study uses DNA origami ...

Due to their nanoprecise spacing of adjuvant molecules (shown as green ribbons on one face of their squareblock structures), DoriVac vaccines, after being taken up by antigen-presenting immune cells, ...

The COVID-19 pandemic brought messenger RNA (mRNA) vaccines to the forefront of global health care. After their clinical trial stages, the first COVID-19 mRNA vaccine was administered on 8 December ...