A research team led by investigators at McMaster University has identified an axonal guidance signaling pathway that cancer cells use to infiltrate the brain. The combined results of preclinical in ...

Researchers from the Icahn School of Medicine at Mount Sinai have discovered a molecular switch in neurons that limits the ...

Axonal degeneration and neuroinflammation are increasingly recognised as pivotal processes in the pathogenesis of neurodegenerative diseases. Axonal degeneration refers to the progressive ...

In a bid to better understand, and potentially treat, a host of conditions that affect early cognition, neurodevelopment, and ...

A cross-sectional image of the mouse cerebral cortex in enlargement. The same method was applied as in the ferret. The cerebral cortex is shown in blue and some neurons are dyed green with GFP. In ...

A major discovery reveals that metformin works not just in the body, but in the brain. By switching off a key protein and activating specific neurons, the drug lowers blood sugar through a previously ...

Understanding how the brain works requires more than studying single regions in isolation. The cerebral cortex depends on long-distance connections that link specialized areas into coordinated ...